Alcoholic hepatitis: The pivotal role of Kupffer cells
نویسندگان
چکیده
منابع مشابه
Alcoholic hepatitis: The pivotal role of Kupffer cells.
Kupffer cells play a central role in the pathogenesis of alcoholic hepatitis (AH). It is believed that alcohol increases the gut permeability that results in raised levels of serum endotoxins containing lipopolysaccharides (LPS). LPS binds to LPS-binding proteins and presents it to a membrane glycoprotein called CD14, which then activates Kupffer cells via a receptor called toll-like receptor 4...
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ژورنال
عنوان ژورنال: World Journal of Gastrointestinal Pathophysiology
سال: 2015
ISSN: 2150-5330
DOI: 10.4291/wjgp.v6.i4.90